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<i>In Silico</i> Simulations Reveal Molecular Mechanism of Uranyl Ion Toxicity towards DNA-Binding Domain of PARP-1 Protein

The molecular toxicity of the uranyl ion (UO<sub>2</sub><sup>2+</sup>) in living cells is primarily determined by its high affinity to both native and potential metal-binding sites that commonly occur in the structure of biomolecules. Recent advances in computational and experimental research have s...

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Bibliografiske detaljer
Principais autores: Egor S. Bulavko, Marina A. Pak, Dmitry N. Ivankov
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-08-01
Serier:Biomolecules
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Online adgang:https://www.mdpi.com/2218-273X/13/8/1269
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