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Combined metabolome and transcriptome to analyze the regulatory network of key enzymes in the synthesis of senkirkine in Emilia sonchifolia

Abstract Emilia sonchifolia (L.) DC. serves as a well-known folk medicinal and edible plant, yet its toxic component senkirkine exhibits hepatotoxicity. Acute high-dose exposure can induce sinusoidal obstruction syndrome, while chronic low-dose intake may cause hepatic megaloblastosis and fibrosis....

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Principais autores: Jinli Yao, Yanqing Qin, Dongping Tu, Yumei Huang, Liuguan Liang, Wenhui Cai, Mingli Huang, Xiaoqi Zhu, Xinling Lao
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-08-01
Serier:BMC Plant Biology
Fag:
Emilia sonchifolia
Senkirkine
Metabolome
Transcriptome
QRT-PCR
Online adgang:https://doi.org/10.1186/s12870-025-07079-4
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