Effects of Isoxazolyl Steroids on Key Genes of Sonic Hedgehog Cascade Expression in Tumor Cells

Activation of the Hedgehog (Hh) signaling pathway is often associated with the progression of various types of cancer. The purpose of study was to search for inhibitors of the Hh signaling pathway among eight compounds belonging to the group of isoxazolyl steroids. The evaluation of the effectivenes...

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Autori principali:	Anna Aleksandrova, Arif Mekhtiev, Olga Timoshenko, Elena Kugaevskaya, Tatiana Gureeva, Alisa Gisina, Maria Zavialova, Kirill Scherbakov, Anton Rudovich, Vladimir Zhabinskii, Vladimir Khripach
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2024-08-01
Serie:	Molecules
Soggetti:	steroids isoxazoles Hh receptors cancer cell proliferation MMP
Accesso online:	https://www.mdpi.com/1420-3049/29/17/4026
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