Lactate-mediated macrophage polarization promotes splenomegaly in acute erythroleukemia
Abstract Acute erythroleukemia (AEL) is a rare and highly aggressive subtype of acute myeloid leukemia (AML) that is often accompanied by splenomegaly in some patients. Using the Friend murine leukemia virus clone 57 (F-MuLV clone 57) mouse model, we observed lactate accumulation in the spleens of m...
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| Principais autores: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2026-03-01
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| Serier: | Cell Death and Disease |
| Online adgang: | https://doi.org/10.1038/s41419-026-08612-5 |
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