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The mini-chromosome maintenance (Mcm) complexes interact with DNA polymerase α-primase and stimulate its ability to synthesize RNA primers.

The Mini-chromosome maintenance (Mcm) proteins are essential as central components for the DNA unwinding machinery during eukaryotic DNA replication. DNA primase activity is required at the DNA replication fork to synthesize short RNA primers for DNA chain elongation on the lagging strand. Although...

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Bibliografische gegevens
Hoofdauteurs: Zhiying You, Mariarosaria De Falco, Katsuhiko Kamada, Francesca M Pisani, Hisao Masai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2013-01-01
Reeks:PLoS ONE
Online toegang:http://europepmc.org/articles/PMC3748026?pdf=render
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