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synDNA—a Synthetic DNA Spike-in Method for Absolute Quantification of Shotgun Metagenomic Sequencing

ABSTRACT Microbiome studies have the common goal of determining which microbial taxa are present, respond to specific conditions, or promote phenotypic changes in the host. Most of these studies rely on relative abundance measurements to drive conclusions. Inherent limitations of relative values are...

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Bibliografiske detaljer
Principais autores: Livia S. Zaramela, Megan Tjuanta, Oriane Moyne, Maxwell Neal, Karsten Zengler
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2022-12-01
Serier:mSystems
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Online adgang:https://journals.asm.org/doi/10.1128/msystems.00447-22
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