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Study protocol: short against long antibiotic therapy for infected orthopedic sites — the randomized-controlled SALATIO trials

Abstract Background Few studies address the appropriate duration of post-surgical antibiotic therapy for orthopedic infections; with or without infected residual implants. We perform two similar randomized-clinical trials (RCT) to reduce the antibiotic use and associated adverse events. Methods Two...

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Principais autores: Ilker Uçkay, Stephan Wirth, Björn Zörner, Sandro Fucentese, Karl Wieser, Andreas Schweizer, Daniel Müller, Patrick Zingg, Mazda Farshad
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-02-01
Serier:Trials
Fag:
Orthopedic infections
Osteomyelitis
Surgical debridement
Antibiotic duration
Remission
Adverse events
Online adgang:https://doi.org/10.1186/s13063-023-07141-2
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