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The Added Value of Whole-Exome Sequencing for Anomalous Fetuses With Detailed Prenatal Ultrasound and Postnatal Phenotype

ObjectivesThe objective of the study was to explore the added value of whole-exome sequencing (WES) in abnormal fetuses with detailed prenatal ultrasound and postnatal phenotype with normal karyotype and chromosomal microarray analysis (CMA).MethodsParents of fetuses with structural abnormalities by...

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Principais autores: Miao He, Liu Du, Hongning Xie, Lihe Zhang, Yujun Gu, Ting Lei, Ju Zheng, Dan Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-07-01
coleção:Frontiers in Genetics
Assuntos:
whole-exome sequencing
anomalous fetuses
prenatal ultrasound
postnatal phenotype
genetic variants
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fgene.2021.627204/full
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