Ganglioside GT1b prevents selective spinal synapse removal following peripheral nerve injury

Abstract After peripheral nerve injury, the structure of the spinal cord is actively regulated by glial cells, contributing to the chronicity of neuropathic pain. However, the mechanism by which peripheral nerve injury leads to synaptic imbalance remains elusive. Here, we use a pH-reporter system an...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Jaesung Lee, Kyungchul Noh, Subeen Lee, Kwang Hwan Kim, Seohyun Chung, Hyoungsub Lim, Minkyu Hwang, Joon-Hyuk Lee, Won-Suk Chung, Sunghoe Chang, Sung Joong Lee
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Springer Nature 2025-04-01
Цуврал:	EMBO Reports
Нөхцлүүд:	Neuropathic Pain Microglia Astrocyte Synapse Phagocytosis GT1b
Онлайн хандалт:	https://doi.org/10.1038/s44319-025-00452-2
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!