Growth hormone receptor promotes osteosarcoma cell growth and metastases

Osteosarcoma (OS) is the primary bone malignancy in children and adolescents, with a high incidence of lung metastasis and poor prognosis. Here, we report that growth hormone receptor (GHR) is overexpressed in OS samples compared with osteofibrous dysplasia. We subsequently demonstrated that GHR kno...

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Bibliografiske detaljer

Principais autores:	Mo Cheng, Wending Huang, Weiluo Cai, Meng Fang, Yong Chen, Chunmeng Wang, Wangjun Yan
Format:	Artigo
Sprog:	Inglês
Udgivet:	Wiley 2020-01-01
Serier:	FEBS Open Bio
Fag:	growth hormone receptor metastasis osteosarcoma proliferation tumor growth
Online adgang:	https://doi.org/10.1002/2211-5463.12761
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