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New Chemical Probe Targeting Bacterial NAD Kinase

Nicotinamide adenine dinucleotide (NAD) kinases are essential and ubiquitous enzymes involved in the tight regulation of NAD/nicotinamide adenine dinucleotide phosphate (NADP) levels in many metabolic pathways. Consequently, they represent promising therapeutic targets in cancer and antibacterial tr...

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Guardado en:
Autores principales: David A. Clément, Clarisse Leseigneur, Muriel Gelin, Dylan Coelho, Valérie Huteau, Corinne Lionne, Gilles Labesse, Olivier Dussurget, Sylvie Pochet
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2020-10-01
Colección:Molecules
Materias:
antibiotics
chemical probe
diadenosine derivatives
NAD kinase
nucleoside
Sonogashira coupling
Acceso en línea:https://www.mdpi.com/1420-3049/25/21/4893
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