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CTGF promotes the repair and regeneration of alveoli after acute lung injury by promoting the proliferation of subpopulation of AEC2s

Abstract Background Functional alveolar regeneration is essential for the restoration of normal lung homeostasis after acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Lung is a relatively quiescent organ and a variety of stem cells are recruited to participate in lung repair...

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Principais autores: Jianhui Sun, Huacai Zhang, Di Liu, Wenyi Liu, Juan Du, Dalin Wen, Luoxi Li, Anqiang Zhang, Jianxin Jiang, Ling Zeng
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-09-01
Serier:Respiratory Research
Fag:
Acute lung injury
Acute respiratory distress syndrome
Alveolar regeneration
Connective tissue growth factor
Alveolar epithelial type 2 cells
Alveolar epithelial type 1 cells
Online adgang:https://doi.org/10.1186/s12931-023-02512-4
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