Machine learning identifies molecular regulators and therapeutics for targeting SARS‐CoV2‐induced cytokine release

Abstract Although 15–20% of COVID‐19 patients experience hyper‐inflammation induced by massive cytokine production, cellular triggers of this process and strategies to target them remain poorly understood. Here, we show that the N‐terminal domain (NTD) of the SARS‐CoV‐2 spike protein substantially i...

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Autores principales:	Marina Chan, Siddharth Vijay, John McNevin, M Juliana McElrath, Eric C Holland, Taranjit S Gujral
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Springer Nature 2021-09-01
Colección:	Molecular Systems Biology
Materias:	kinases machine learning N‐terminal domain Ponatinib SARS‐CoV‐2
Acceso en línea:	https://doi.org/10.15252/msb.202110426
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