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The role of the PKCζ/JNK signaling pathway in regulating the development of femoral head necrosis

Osteonecrosis of the femoral head (ONFH) is a debilitating condition characterized by the death of bone cells in the hip joint, resulting in profound disability. This condition has a significant global prevalence. Glucocorticoid (GC)-induced apoptosis of bone cells serves as a crucial cellular mecha...

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Principais autores: Miaofeng Hu, Cheng Li, Qi Sun, Baisong Hu, Jiong Yang, Xiufeng Wang, Jinshan Huang, Di Shen
Format: Artigo
Sprog:Inglês
Udgivet: Associação Brasileira de Divulgação Científica 2025-03-01
Serier:Brazilian Journal of Medical and Biological Research
Fag:
Osteonecrosis of the femoral head
Glucocorticoid
Osteoblast apoptosis
PKCζ
JNK
Online adgang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2025000100622&lng=en&tlng=en
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