Clinical utility of sarcoma methylation classifiers in soft tissue sarcoma diagnosis

Abstract Purpose Soft tissue sarcomas are rare malignant tumors of mesenchymal origin characterized by their heterogeneity and diagnosis is challenging despite integrated histopathology and molecular testing. DNA methylation profiling offers an objective approach for tumor classification, but clinic...

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Hlavní autoři:	Justus Osterloh, David E. Reuss, Andreas von Deimling, Hannah Füllgraf, Jannis Heyer, Konrad Kurowski, Clara Kirchhof, Anna Meiertoberens, Ute Lausch, Adrian Schmid, Steffen U. Eisenhardt, David Braig, Alexander Runkel
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer 2026-05-01
Edice:	Journal of Cancer Research and Clinical Oncology
Témata:	Soft tissue sarcoma DNA methylation Tumor classifier Molecular diagnostics
On-line přístup:	https://doi.org/10.1007/s00432-026-06494-w
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