Synthesis and Biological Evaluation of Thieno[3,2-d]- pyrimidinones, Thieno[3,2-d]pyrimidines and Quinazolinones: Conformationally Restricted 17b-Hydroxysteroid Dehydrogenase Type 2 (17b-HSD2) Inhibitors

In this study, a series of conformationally restricted thieno[3,2-d]pyrimidinones, thieno[3,2-d]pyrimidines and quinazolinones was designed and synthesized with the goal of improving the biological activity as 17b-hydroxysteroid dehydrogenase type 2 inhibitors of the corresponding amidothiophene der...

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Egile Nagusiak:	Rolf W. Hartmann, Enrico Perspicace, Sandrine Marchais-Oberwinkler
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2013-04-01
Saila:	Molecules
Gaiak:	thieno[3,2-d]pyrimidinones thieno[3,2-d]pyrimidines quinazolinones conformationally restricted analogues enzyme inhibitors 17b-hydroxysteroid dehydrogenase type 2 osteoporosis
Sarrera elektronikoa:	http://www.mdpi.com/1420-3049/18/4/4487
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