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Molecular Mechanism of the IRF1/NFE2L1‐DT/ALKBH5/Cx43 Axis in Radiation‐Induced Injury in Vascular Endothelial Cells Through Pyroptosis

ABSTRACT Radiotherapy effectively eradicates tumor cells but can also trigger pyroptotic damage in vascular endothelial cells. This study investigates the role of interferon regulatory factor 1 (IRF1) in radiation‐induced endothelial injury, aiming to provide mechanistic insights for optimizing radi...

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Autors principals: Chen Li, Jia‐Wen Yang, Yong‐Rui Jia, Jie Zhang, Qiao Gou
Format: Artigo
Idioma:Inglês
Publicat: Wiley 2026-07-01
Col·lecció:Kaohsiung Journal of Medical Sciences
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Accés en línia:https://doi.org/10.1002/kjm2.70159
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