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IL-1β mediates Candida tropicalis-induced immunosuppressive function of MDSCs to foster colorectal cancer

Abstract Background There is increasing evidence that gut fungi dysbiosis plays a crucial role in the development and progression of colorectal cancer (CRC). It has been reported that gut fungi exacerbate the severity of CRC by regulating tumor immunity. Our previous studies have shown that the oppo...

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Principais autores: Zhiyong Zhang, Ying Chen, Xinyi Pan, Pengfei Li, Zhengqian Ren, Xiuzhu Wang, Yuxi Chen, Sunan Shen, Tingting Wang, Aihua Lin
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-08-01
Serier:Cell Communication and Signaling
Fag:
CRC
Candida tropicalis
MDSCs
NLRP3
IL-1β
Online adgang:https://doi.org/10.1186/s12964-024-01771-y
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