Comparative Investigation of R213G Mutation in DNA-Binding Domain of P53 Protein via Molecular Dynamics Simulation

Introduction: P53 is a tumor suppressor protein with numerous missense mutations identified in its gene. These mutations are observed in a vast number of cancers. R213G is one of them which has a role in metastatic lung cancers. In this research, R213G was studied in comparison with the wild type vi...

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Hlavní autoři:	Elham Akbari, Mohammad Taghizadeh, Fahimeh Nemati
Médium:	Artigo
Jazyk:	Persa
Vydáno:	Kerman University of Medical Sciences 2021-06-01
Edice:	مجله انفورماتیک سلامت و زیست پزشکی
Témata:	root mean square fluctuation (rmsf) protein flexibility p53 protein missense mutation molecular dynamics simulation
On-line přístup:	http://jhbmi.ir/article-1-524-en.html
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