Evolving Roles for Targeting CTLA-4 in Cancer Immunotherapy
Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is a membrane glycoprotein expressed by activated effector T cells (Teffs) and participates in the repression of T cell proliferation, cell cycle progression and cytokine production. Currently, antibodies targeting CTLA-4, ipilimumab and tremelimu...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cell Physiol Biochem Press GmbH & Co KG
2018-05-01
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| Col·lecció: | Cellular Physiology and Biochemistry |
| Matèries: | |
| Accés en línia: | https://www.karger.com/Article/FullText/490025 |
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