Selenium Status in Diet Affects Nephrotoxicity Induced by Cisplatin in Mice

Cisplatin is one of the most active chemotherapy drugs to treat solid tumors. However, it also causes various side effects, especially nephrotoxicity, in which oxidative stress plays critical roles. Our previous studies found that cisplatin selectively inhibited selenoenzyme thioredoxin reductase1 (...

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Autors principals:	Shuang Liu, Xing Wen, Qihan Huang, Minghui Zhu, Jun Lu
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-06-01
Col·lecció:	Antioxidants
Matèries:	cisplatin nephrotoxicity oxidative stress thioredoxin selenium selenoprotein
Accés en línia:	https://www.mdpi.com/2076-3921/11/6/1141
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