Exploring the Potential of Site-Selective Labeling on a Green Fluorescent Protein Through Lys–His Linchpin-Directed Modification

Protein-based biosensors require controlled and site-selective functionalization strategies to enable stable and oriented immobilization without compromising protein structure and signal transduction efficiency. We evaluated a chemoselective linchpin-directed modification (LDM) approach targeting Ly...

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Autors principals:	Stefania Bova, Marialaura Marchetti, Ilaria De Nardis, Serena Faggiano, Samanta Raboni, Alessandra Gritti, Elisa Pianta, Valentina Pirovano, Giorgio Abbiati, Gloria Modafferi, Barbara Pioselli, Stefano Bruno, Barbara Campanini, Stefano Bettati, Luca Ronda
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2026-06-01
Col·lecció:	Sensors
Matèries:	protein biosensors green fluorescent protein (GFP) site-selective labeling linchpin-directed modification (LDM)
Accés en línia:	https://www.mdpi.com/1424-8220/26/13/4095
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