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A substrate-fusion protein is trapped inside the Type III Secretion System channel in Shigella flexneri.

The Type III Secretion System (T3SS) is a macromolecular complex used by Gram-negative bacteria to secrete effector proteins from the cytoplasm across the bacterial envelope in a single step. For many pathogens, the T3SS is an essential virulence factor that enables the bacteria to interact with and...

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Autori principali: Kim Dohlich, Anna Brotcke Zumsteg, Christian Goosmann, Michael Kolbe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS Pathogens
Accesso online:http://europepmc.org/articles/PMC3894212?pdf=render
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