A novel sphingosylphosphorylcholine and sphingosine-1-phosphate receptor 1 antagonist, KRO-105714, for alleviating atopic dermatitis

Abstract Background Atopic dermatitis (eczema) is a type of inflammation of the skin, which presents with itchy, red, swollen, and cracked skin. The high global incidence of atopic dermatitis makes it one of the major skin diseases threatening public health. Sphingosylphosphorylcholine (SPC) and sph...

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Hlavní autoři:	Sae-Bom Yoon, Chang Hoon Lee, Hyun Young Kim, Daeyoung Jeong, Moon Kook Jeon, Sun-A Cho, Kwangmi Kim, Taeho Lee, Jung Yoon Yang, Young-Dae Gong, Heeyeong Cho
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2020-05-01
Edice:	Journal of Inflammation
Témata:	Sphingosylphosphorylcholine Sphingosine-1-phosphate receptor 1 Antagonist Anti-inflammatory Atopic dermatitis High-throughput screening
On-line přístup:	http://link.springer.com/article/10.1186/s12950-020-00244-6
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