Antimicrobial activity of human prion protein is mediated by its N-terminal region.

BACKGROUND: Cellular prion-related protein (PrP(c)) is a cell-surface protein that is ubiquitously expressed in the human body. The multifunctionality of PrP(c), and presence of an exposed cationic and heparin-binding N-terminus, a feature characterizing many antimicrobial peptides, made us hypothes...

詳細記述

書誌詳細

主要な著者:	Mukesh Pasupuleti, Markus Roupe, Victoria Rydengård, Krystyna Surewicz, Witold K Surewicz, Anna Chalupka, Martin Malmsten, Ole E Sörensen, Artur Schmidtchen
フォーマット:	Artigo
言語:	Inglês
出版事項:	Public Library of Science (PLoS) 2009-01-01
シリーズ:	PLoS ONE
オンライン･アクセス:	http://europepmc.org/articles/PMC2752989?pdf=render
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