YAP, ΔNp63, and β-Catenin Signaling Pathways Are Involved in the Modulation of Corneal Epithelial Stem Cell Phenotype Induced by Substrate Stiffness

Recent studies have established that the phenotype of epithelial stem cells residing in the corneal periphery (the limbus) depends on this niche’s distinct biomechanical properties. However, the signaling pathways underlying this dependency are still poorly understood. To address this issue, w...

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Detalhes bibliográficos

Principais autores:	Ricardo M. Gouveia, Flora Vajda, Jason A. Wibowo, Francisco Figueiredo, Che J. Connon
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2019-04-01
coleção:	Cells
Assuntos:	tissue stiffness limbal epithelial stem cells mechanotransduction epithelial stratification β-Catenin signaling fibrosis
Acesso em linha:	https://www.mdpi.com/2073-4409/8/4/347
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