Endothelium-Mimetic Surface Modification Improves Antithrombogenicity and Enhances Patency of Vascular Grafts in Rats and Pigs

Summary: We first identified thrombomodulin (TM) and endothelial nitric oxide (NO) synthase as key factors for the antithrombogenic function of the endothelium in human atherosclerotic carotid arteries. Then, recombinant TM and an engineered galactosidase responsible for the conversion of an exogeno...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Yongzhen Wei, PhD, Huan Jiang, BS, Chao Chai, MD, Pei Liu, MS, Meng Qian, PhD, Na Sun, MD, Man Gao, MS, Honglin Zu, MD, Yongquan Yu, MD, Guangbo Ji, BS, Yating Zhang, BS, Sen Yang, MD, Ju He, MD, Jiansong Cheng, PhD, Jinwei Tian, MD, PhD, Qiang Zhao, PhD
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2023-07-01
Σειρά:	JACC: Basic to Translational Science
Θέματα:	antithrombogenic surface modification endothelialization nitric oxide thrombomodulin vascular grafts
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S2452302X23000050
Ετικέτες:	Προσθήκη ετικέτας Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!