Elucidating functional epitopes within the N-terminal region of malaria transmission blocking vaccine antigen Pfs230

Abstract Pfs230 is a leading malaria transmission blocking vaccine (TBV) candidate. Comprising 3135 amino acids (aa), the large size of Pfs230 necessitates the use of sub-fragments as vaccine immunogens. Therefore, determination of which regions induce functional antibody responses is essential. We...

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Autors principals:	Kazutoyo Miura, Eizo Takashima, Thao P. Pham, Bingbing Deng, Luwen Zhou, Wei-Chiao Huang, Ababacar Diouf, Yonas T. Gebremicale, Mayumi Tachibana, Tomoko Ishino, C. Richter King, Jonathan F. Lovell, Carole A. Long, Takafumi Tsuboi
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2022-01-01
Col·lecció:	npj Vaccines
Accés en línia:	https://doi.org/10.1038/s41541-021-00423-3
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