Optimization and Evaluation of Poly(lactide-<i>co</i>-glycolide) Nanoparticles for Enhanced Cellular Uptake and Efficacy of Paclitaxel in the Treatment of Head and Neck Cancer

The particle size (PS) and encapsulation efficiency (EE%) of drug-loaded nanoparticles (NPs) may inhibit their cellular uptake and lead to possible leakage of the drug into the systemic circulation at the tumor site. In this work, ultra-high paclitaxel-loaded poly(lactide-<i>co</i>-glycolide) NPs (P...

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Principais autores:	Mohamed Haider, Amr Elsherbeny, Jayalakshmi Jagal, Anna Hubatová-Vacková, Iman Saad Ahmed
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2020-08-01
Serija:	Pharmaceutics
Teme:	paclitaxel poly(lactide-<i>co</i>-glycolide) nanoparticles quality-by-design head and neck cancer
Online dostop:	https://www.mdpi.com/1999-4923/12/9/828
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