Lipoic acid promotes SIRT1 and SIRT4 and mitochondrial biogenesis in skeletal and heart muscles of broilers

Alpha-lipoic acid (ALA) improves feed conversion in broilers in a dose-dependent manner, but its key effects on metabolism are not known. In this study, we characterized in broilers the effects of ALA on the expression and activity of Sirtuin 1 (SIRT1) and Sirtuin 4 (SIRT4) and on mitochondrial biog...

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Autors principals:	Sergio Sigler-Galván, Alejandra Domínguez-Negrete, Laura González-Dávalos, Adriana González-Gallardo, Alfonso Cárabez, Maricela Luna-Muñoz, Martha Carranza-Salas, Carlos Lozano-Flores, Alfredo Varela-Echavarria, Armando Shimada, Enrique Piña, Ofelia Mora
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis Group 2026-12-01
Col·lecció:	Journal of Applied Animal Research
Matèries:	Alpha-lipoic acid broilers heart and skeletal muscle mitochondrial biogenesis sirtuins
Accés en línia:	https://www.tandfonline.com/doi/10.1080/09712119.2026.2695161
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