The redox driven Na+-pumping mechanism in Vibrio cholerae NADH-quinone oxidoreductase relies on dynamic conformational changes

Abstract The Na+-pumping NADH-quinone oxidoreductase (Na+-NQR) is a key respiratory enzyme in many marine and pathogenic bacteria that couples electron transfer to Na+-pumping across the membrane. Earlier X-ray and cryo-electron microscopy structures of Na+-NQR from Vibrio cholerae suggested that th...

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Detalhes bibliográficos

Principais autores:	Moe Ishikawa-Fukuda, Takehito Seki, Jun-ichi Kishikawa, Takahiro Masuya, Kei-ichi Okazaki, Takayuki Kato, Blanca Barquera, Hideto Miyoshi, Masatoshi Murai
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-02-01
Colecção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-026-69182-w
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