QR-Code

Development of mRNA–lipid nanoparticle intrabodies against rickettsial infection

Abstract Background Rickettsiosis is among the deadliest vector-borne infectious diseases worldwide, in part because rickettsiae replicate within human cells, where antibodies and most drugs cannot effectively reach this obligatory intracellular pathogen. Ehrlichia chaffeensis, an emerging rickettsi...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Qi Yan, Nan Duan, Mingqun Lin, Wenqing Zhang, Stephen Denton, Yichen Zhong, Yizhou Dong, Yasuko Rikihisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2025-08-01
Schriftenreihe:Journal of Biomedical Science
Schlagworte:
Ehrlichia chaffeensis
Rickettsia
Anti–Etf-2
Intrabody
Endosome
RAB5
Online-Zugang:https://doi.org/10.1186/s12929-025-01171-5
Tags: Tag hinzufügen
Keine Tags, Fügen Sie das erste Tag hinzu!

Ähnliche Einträge