Loss of Bacteroides thetaiotaomicron bile acid-altering enzymes impacts bacterial fitness and the global metabolic transcriptome

ABSTRACT Bacteroides thetaiotaomicron (B. theta) is a Gram-negative gut bacterium that encodes enzymes that alter the bile acid pool in the gut. Primary bile acids are synthesized by the host liver and are modified by gut bacteria. B. theta encodes two bile salt hydrolases, as well as a hydroxystero...

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Autori principali:	Arthur S. McMillan, Matthew H. Foley, Caroline E. Perkins, Casey M. Theriot
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2024-01-01
Serie:	Microbiology Spectrum
Soggetti:	bile acids Bacteroides thetaiotaomicron bile salt hydrolase hydroxysteroid dehydrogenase carbohydrates amino acids
Accesso online:	https://journals.asm.org/doi/10.1128/spectrum.03576-23
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