Bone marrow mesenchymal stem cell-derived exosomes alleviate DSS-induced inflammatory bowel disease in mice through inhibiting intestinal epithelial cell pyroptosis via delivery of TSG-6

BackgroundInflammatory bowel disease (IBD), characterized by chronic intestinal inflammation and epithelial barrier dysfunction, remains a therapeutic challenge due to the limitations of current treatments, including drug resistance and invasive surgical risks. Emerging evidence implicates intestina...

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Үндсэн зохиолчид:	Bihua Wu, Shuangyan Su, Xianyu Wang, Yuwei Li, Zhenghao Mei, Fenglin Lou, Le Guo
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2025-06-01
Цуврал:	Frontiers in Immunology
Нөхцлүүд:	inflammatory bowel disease bone marrow mesenchymal stem cells exosomes pyroptosis intestinal epithelial cells TSG-6
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1601591/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!