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Clinical and mechanistic insights into the expression of SP100 family proteins in various cancers: a systematic review

Abstract Introduction Cancer remains a leading global health burden, with projections estimating 35 million new cases by 2050. The Speckled Protein 100 (SP100) family, comprising SP100, SP110, SP140, and SP140L, has emerged as a critical player in cancer biology due to their roles in transcriptional...

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Principais autores: Mehrnoosh Azami, Fatemeh Sadeghi, Nazanin Mohammadi, Zahra Sadat Shayegh, Arshia Hassanzadeh, Mohammad Javad Heidarzadeh, Armin ZarinKhat, Zhina Mohamadi
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-11-01
Serier:BMC Cancer
Fag:
Cancer
Neoplasm
SP100
SP140
SP110
SP140L
Online adgang:https://doi.org/10.1186/s12885-025-15159-9
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