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ICP8-vhs- HSV-2 Vaccine Expressing B7 Costimulation Molecules Optimizes Safety and Efficacy against HSV-2 Infection in Mice

Herpes simplex virus 2 (HSV-2) causes most sexually transmitted genital ulcerative disease. No effective prophylactic vaccine is currently available. Replication-defective (ICP8-) HSV stimulates immune responses in animals without producing progeny virus, making it potentially useful as a safe form...

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Bibliografiska uppgifter
Huvudupphov: Maria Korom, Hong Wang, Kaelin M. Bernier, Brian J. Geiss, Lynda A. Morrison
Materialtyp: Artigo
Språk:Inglês
Utgiven: MDPI AG 2023-07-01
Serie:Viruses
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Länkar:https://www.mdpi.com/1999-4915/15/7/1570
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