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NRF2 Mediates Therapeutic Resistance to Chemoradiation in Colorectal Cancer through a Metabolic Switch

Radiation resistance is a significant clinical problem in rectal cancer treatment, the mechanisms of which are poorly understood. NRF2 signalling is known to contribute to chemo/radioresistance in some cancers, but its role in therapeutic resistance in colorectal cancer (CRC) is unexplored. Using si...

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Bibliografiske detaljer
Principais autores: Séan M. O’Cathail, Chieh-Hsi Wu, Rachael Thomas, Maria A. Hawkins, Tim S. Maughan, Annabelle Lewis
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-08-01
Serier:Antioxidants
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Online adgang:https://www.mdpi.com/2076-3921/10/9/1380
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