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Sputum microbiome α-diversity is a key feature of the COPD frequent exacerbator phenotype

Background The lung microbiome is an inflammatory stimulus whose role in COPD pathogenesis is incompletely understood. We hypothesised that the frequent exacerbator phenotype is associated with decreased α-diversity and increased lung inflammation. Our objective was to assess correlations between th...

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Бібліографічні деталі
Автори: Alexa A. Pragman, Shane W. Hodgson, Tianhua Wu, Allison Zank, Cavan S. Reilly, Chris H. Wendt
Формат: Artigo
Мова:Inglês
Опубліковано: European Respiratory Society 2024-02-01
Серія:ERJ Open Research
Онлайн доступ:http://openres.ersjournals.com/content/10/1/00595-2023.full
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