Optimizing antifungal dosing for invasive Cryptococcus infections: minimum inhibitory concentration distributions and pharmacokinetic/pharmacodynamic insights from 2010–2023 Antimicrobial Testing Leadership and Surveillance data

ObjectiveThe 2024 global cryptococcosis treatment guidelines suggests that fluconazole (FLC) combined with liposomal amphotericin B (AMB) and 5-flucytosine (5-FC) as the mainstay of treatment for systemic cryptococcosis. Although this 2024 guidelines also list recommend voriconazole (VRC), posaconaz...

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Автори:	Chia-Ying Liu, Chih-Cheng Lai, Chun-Chung Hsueh, Chih-Jen Weng, Wei-Lun Chang, Po-Ren Hsueh, Shio-Shin Jean
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Frontiers Media S.A. 2025-10-01
Серія:	Frontiers in Pharmacology
Предмети:	Cryptococcus species fluconazole voriconazole posaconazole isavuconazole liposomal amphotericin B
Онлайн доступ:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1665253/full
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