A mouse model of stereotactic radiosurgery-induced neuroinflammation and blood-brain barrier compromise

Abstract Stereotactic radiosurgery (SRS) is a procedure that delivers high-dose single fraction, targeted radiation to treat brain pathologies. Brain radiation necrosis is a significant side effect of SRS, resulting in severe clinical sequelae such as seizure, hemorrhage, stroke, and neurological de...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Roberto J. Alcazar-Felix, Lin Cheng, Abhinav Srinath, Akash Bindal, David Tieri, Diana Vera-Cruz, Madison Yuan, Sammy Allaw, Nitha Aima Muntu, Dominic Montas, András Piffkó, Erik Pearson, Bader Ali, Peter Pytel, Issam A. Awad, Sean P. Polster
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2025-09-01
Serija:	Acta Neuropathologica Communications
Teme:	Stereotactic radiosurgery (SRS) Adverse radiation effects (AREs) Brain damage Mouse radiation model Neurovascular unit Blood-brain barrier (BBB)
Online dostop:	https://doi.org/10.1186/s40478-025-02112-x
Oznake:	Označite Brez oznak, prvi označite!