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Chiral phosphoric acid-catalyzed atroposelective iodination of N-arylindoles

Abstract Axially chiral indoles have garnered significant attention due to their synthetic and biological importance. However, atroposelective halogenation of this scaffold has been rarely explored. This study presents a catalytic and enantioselective iodination of N-arylindoles, achieving precise c...

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Auteurs principaux: Ahreum Kim, Hyun-A Cho, Byeongjun Oh, Jayoung Song, Yongseok Kwon
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2025-06-01
Collection:Communications Chemistry
Accès en ligne:https://doi.org/10.1038/s42004-025-01584-1
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