Single mutation at a highly conserved region of chloramphenicol acetyltransferase enables isobutyl acetate production directly from cellulose by Clostridium thermocellum at elevated temperatures

Abstract Background Esters are versatile chemicals and potential drop-in biofuels. To develop a sustainable production platform, microbial ester biosynthesis using alcohol acetyltransferases (AATs) has been studied for decades. Volatility of esters endows high-temperature fermentation with advantage...

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Autores principales:	Hyeongmin Seo, Jong-Won Lee, Sergio Garcia, Cong T. Trinh
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2019-10-01
Colección:	Biotechnology for Biofuels
Materias:	Alcohol acetyltransferase Thermostability Chloramphenicol acetyltransferase Isobutyl acetate Esters Consolidated bioprocessing
Acceso en línea:	http://link.springer.com/article/10.1186/s13068-019-1583-8
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