Radiosynthesis of a novel antisense imaging probe targeting LncRNA HOTAIR in malignant glioma

Abstract Background Long non-coding RNA (LncRNA) HOTAIR was amplified and overexpressed in many human carcinomas, which could serve as a useful target for cancer early detection and treatment. The 99mTc radiolabeled antisense oligonucleotides (ASON) could visualize the expression of HOTAIR and provi...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Jiongyu Ren, Xiyuan Zhang, Jiang Cao, Jiali Tian, Jin Luo, Yaping Yu, Fengkui Wang, Qian Zhao
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2022-01-01
Σειρά:	BMC Cancer
Θέματα:	LncRNA HOTAIR Antisense oligonucleotide probe Malignant glioma SPECT imaging
Διαθέσιμο Online:	https://doi.org/10.1186/s12885-022-09170-7
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