Single-cell and multi-omics analysis reveals the role of stem cells in prognosis and immunotherapy of lung adenocarcinoma patients

BackgroundThe roles of stem cells in lung adenocarcinoma (LUAD) progression and therapeutic resistance have been recognized, yet their impact on patient prognosis and immunotherapy response remains unclear.MethodsSingle-cell RNA sequencing was performed to identify stem cell populations characterize...

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Главные авторы:	Jianan Zheng, Haoran Lin, Wei Ye, Mingjun Du, Chenjun Huang, Jun Fan
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2025-07-01
Серии:	Frontiers in Immunology
Предметы:	lung adenocarcinoma single-cell sequencing stem cells prognostic model immunotherapy
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1634830/full
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