Bid-Induced Release of AIF/EndoG from Mitochondria Causes Apoptosis of Macrophages during Infection with Leptospira interrogans

Leptospirosis is a global zoonotic infectious disease caused by pathogenic Leptospira species. Leptospire-induced macrophage apoptosis through the Fas/FasL-caspase-8/3 pathway plays an important role in the survival and proliferation of the pathogen in hosts. Although, the release of mitochondrial a...

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Hlavní autoři:	Wei-Lin Hu, Hai-Yan Dong, Yang Li, David M. Ojcius, Shi-Jun Li, Jie Yan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2017-11-01
Edice:	Frontiers in Cellular and Infection Microbiology
Témata:	apoptosis Leptospira Bid AIF EndoG macrophage
On-line přístup:	http://journal.frontiersin.org/article/10.3389/fcimb.2017.00471/full
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