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Identification and classification of ion channels across the tree of life provide functional insights into understudied CALHM channels

The ion channel (IC) genes encoded in the human genome play fundamental roles in cellular functions and disease, and are one of the largest classes of druggable proteins. However, limited knowledge of the diverse molecular and cellular functions carried out by ICs presents a major bottleneck in deve...

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Autors principals: Rahil Taujale, Sung Jin Park, Nathan Gravel, Saber Soleymani, Rayna Carter, Kennady Boyd, Sarah I Keuning, Zheng Ruan, Wei Lü, Natarajan Kannan
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications Ltd 2026-05-01
Col·lecció:eLife
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Accés en línia:https://elifesciences.org/articles/106134
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