Lassa and Mopeia viruses produce different RIG-I-activating RNA in the absence of a functional viral exoribonuclease domain

ABSTRACT All viruses of the genus Mammarenavirus possess an exoribonuclease (ExoN) domain in their nucleoproteins (NP). Through this domain, the NP efficiently prevents the activation of the interferon (IFN) response, presumably by degrading double-stranded RNA (dsRNA) produced during the viral repl...

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Autori principali:	Kodie Noy, Rachel Legendre, Séverine Croze, Valérie Najburg, Romane Fernandez, Julie Lucifora, Joel Lachuer, Sylvain Baize, Anastassia V. Komarova, Mathieu Mateo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2026-06-01
Serie:	Journal of Virology
Soggetti:	viral RNA interferon response RIG-I-like receptors arenaviruses
Accesso online:	https://journals.asm.org/doi/10.1128/jvi.02110-25
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