The causal role between circulating immune cells and diabetic nephropathy: a bidirectional Mendelian randomization with mediating insights

Abstract Diabetic nephropathy (DN) is a critical inflammatory condition linked to diabetes, affecting millions worldwide. This study employs Mendelian randomization (MR) to explore the causal relationship between immune cell signatures and DN, analyzing over 731 immune signatures and incorporating d...

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Hlavní autoři:	Ning Shen, Shangwei Lu, Zhijuan Kong, Ying Gao, Jinxiu Hu, Shuxuan Si, Junlin Wang, Jie Li, Wei Han, Rong Wang, Zhimei Lv
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-07-01
Edice:	Diabetology & Metabolic Syndrome
Témata:	Immune cells Diabetic nephropathy Mendelian randomization Metabolite
On-line přístup:	https://doi.org/10.1186/s13098-024-01386-w
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