Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery

Summary: Cellular homeostasis relies on both the chaperoning of proteins and the intracellular degradation system that delivers cytoplasmic constituents to the lysosome, a process known as autophagy. The crosstalk between these processes and their underlying regulatory mechanisms is poorly understoo...

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Auteurs principaux:	Sarah J. Backe, Rebecca A. Sager, Jennifer A. Heritz, Laura A. Wengert, Katherine A. Meluni, Xavier Aran-Guiu, Barry Panaretou, Mark R. Woodford, Chrisostomos Prodromou, Dimitra Bourboulia, Mehdi Mollapour
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2023-07-01
Collection:	Cell Reports
Sujets:	CP: Molecular biology
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2211124723008185
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