Copper chelation reduces early collagen deposition and preserves saliva secretion in irradiated salivary glands

Radiation therapy is a first-line treatment for head and neck cancer; however, it typically leads to hyposalivation stemming from fibrosis of the salivary gland. Current strategies to restore glandular function are dependent on the presence of residual functional salivary gland tissue, a condition c...

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Detalhes bibliográficos

Principais autores:	Kihoon Nam, Harim Tavares Dos Santos, Frank M. Maslow, Travis Small, Vinit Shanbhag, Michael J. Petris, Olga J. Baker
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-01-01
coleção:	Heliyon
Assuntos:	Head and neck cancer Radiation therapy Hyposalivation Copper chelator Drug delivery Fibrosis
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2405844024003992
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